Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18966668 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TSHRLMNATP53CYP3A4 | |
| SCHEMBL18966632 | 0.99 | TSHR (0.40) | ALDH1A1TSHRLMNATP53CYP3A4 | |
| SCHEMBL18966526 | 0.94 | ALDH1A1 (0.42) | ALDH1A1TSHRLMNATP53CYP3A4 | |
| SCHEMBL21539563 | 0.94 | ALDH1A1 (0.42) | ALDH1A1TSHRLMNATP53CYP3A4 | |
| SCHEMBL18966534 | 0.93 | TSHR (0.41) | ALDH1A1TSHRLMNATP53CYP3A4 | |
| SCHEMBL18966617 | 0.92 | ALDH1A1 (0.40) | ALDH1A1TSHRLMNATP53CYP3A4 | |
| SCHEMBL18966574 | 0.92 | ALDH1A1 (0.40) | ALDH1A1TSHRLMNATP53CYP3A4 | |
| SCHEMBL18966887 | 0.92 | ALDH1A1 (0.42) | ALDH1A1TSHRLMNATP53CYP3A4 | |
| SCHEMBL18966889 | 0.92 | ALDH1A1 (0.42) | ALDH1A1TSHRLMNATP53CYP3A4 | |
| SCHEMBL18966594 | 0.92 | TSHR (0.39) | ALDH1A1TSHRLMNATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10464952-B2 | Beta-lactamase inhibitors | VenatoRx Pharmaceuticals, Inc. (US) | 2019-11-05 | — | — | US | disclosed |
| WO-2017100537-A1 | BETA-LACTAMASE INHIBITORS | VenatoRx Pharmaceuticals, Inc. (US) | 2017-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10464952-B2 | Beta-lactamase inhibitors | MGAM, GAA, LCT | ALDH1A1 305/4885TSHR 4759/4885LMNA 542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.