Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14048605 | 0.82 | ADORA2A (0.59) | PTGER4BCHEACHEKDM4EELANE | |
| SCHEMBL18967423 | 0.79 | ADORA2A (0.40) | ACHEKDM4EELANEADORA2AADORA2B | |
| SCHEMBL4370720 | 0.75 | GLS (0.58) | KDM4EELANEADORA2AADORA2BALDH1A1 | |
| SCHEMBL18967141 | 0.75 | ADORA2A (0.36) | ADORA2AADORA2B | |
| SCHEMBL13202490 | 0.73 | ADORA2A (0.55) | BCHEACHEKDM4EADORA2AADORA2B | |
| SCHEMBL29411837 | 0.72 | HCAR3 (0.47) | PTGER4KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL2800952 | 0.70 | PTGER4 (0.52) | PTGER4KDM4EGRIK2GRIK1ALDH1A1 | |
| SCHEMBL29411826 | 0.70 | HDAC3 (0.47) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL9909981 | 0.69 | CNR2 (0.46) | PTGER4ACHEMAPTRAB9A | |
| SCHEMBL1163076 | 0.69 | CNR1 (0.49) | PTGER4ACHEKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017098328-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHAMACEUTICALS, INC. (BB) | 2017-06-15 | — | — | WO | disclosed |