SCHEMBL18969045

SCHEMBL18969045

c1ccc(C2(c3cccc(N(c4ccc(-c5cccc6ccccc56)cc4)c4ccc(-c5cccc6ccccc56)cc4)c3)c3cccc4ccc5cccc2c5c34)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.36
ACMSD Q8TDX5 1/20 0.36
CA12 O43570 3/20 0.33
CA1 P00915 3/20 0.33
CA2 P00918 3/20 0.33
CA9 Q16790 3/20 0.33
CHRNB4 P30926 2/20 0.33
CHRNA3 P32297 2/20 0.33
CHRNA7 P36544 1/20 0.33
PPARG P37231 9/20 0.33
PPARA Q07869 9/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
CHRNA1 P02708 1/20 0.32
CHRNG P07510 1/20 0.32
CHRNB1 P11230 1/20 0.32
CHRNB2 P17787 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
CHRNA4 P43681 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18969027 0.98 CA12 (0.37) MCL1ACMSDCA12CA1CA2
SCHEMBL18969029 0.93 MCL1 (0.34) MCL1ACMSDCA12CA1CA2
SCHEMBL18969057 0.93 CA12 (0.36) MCL1ACMSDCA12CA1CA2
SCHEMBL18969021 0.92 CA12 (0.40) MCL1ACMSDCA12CA1CA2
SCHEMBL18969023 0.92 CA12 (0.40) MCL1ACMSDCA12CA1CA2
SCHEMBL18287506 0.92 MCL1 (0.39) MCL1ACMSDCA12CA1CA2
SCHEMBL18969032 0.92 CA12 (0.38) MCL1ACMSDCA12CA1CA2
SCHEMBL24882974 0.91 MCL1 (0.38) MCL1ACMSDCA12CA1CA2
SCHEMBL19567723 0.91 MCL1 (0.38) MCL1ACMSDCA12CA1CA2
SCHEMBL18969056 0.91 CA12 (0.37) MCL1ACMSDCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10361374-B2 Amine compound and organic light emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-07-23 US disclosed
US-20170170402-A1 AMINE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-15 US disclosed
US-20170170402-A1 AMINE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170170402-A1 AMINE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME AOC2, MAOA, AOC3 MCL1 3920/4885ACMSD 1072/4885CA12 4774/4885
US-10361374-B2 Amine compound and organic light emitting device including the same AOC2, MAOA, AOC3 MCL1 3920/4885ACMSD 1072/4885CA12 4774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.