SCHEMBL1896953

SCHEMBL1896953

CN(C)c1cccc2c(S(=O)(=O)CCN)cccc12

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.64
CYP1A2 P05177 1/20 0.57
CYP2C19 P33261 1/20 0.57
HTT P42858 1/20 0.57
HIF1A Q16665 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
F2 P00734 3/20 0.55
PRSS1 P07477 3/20 0.55
PRSS2 P07478 3/20 0.55
PRSS3 P35030 3/20 0.55
EDNRA P25101 8/20 0.52
KMT2A Q03164 1/20 0.51
ATM Q13315 1/20 0.51
KDM4E B2RXH2 1/20 0.46
NSD2 O96028 1/20 0.46
TSHR P16473 1/20 0.46
HSD17B10 Q99714 1/20 0.46
APEX1 P27695 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6416698 0.88 CA2 (0.57) CA2CYP1A2CYP2C19HTTHIF1A
SCHEMBL3806560 0.86 CYP1A2 (0.63) CA2CYP1A2CYP2C19HTTHIF1A
SCHEMBL13274117 0.85 CYP1A2 (0.71) CA2CYP1A2CYP2C19HTTHIF1A
SCHEMBL7558145 0.84 CA2 (0.59) CA2CYP1A2CYP2C19HTTHIF1A
SCHEMBL1861706 0.84 CA2 (0.59) CA2CYP1A2CYP2C19HTTHIF1A
SCHEMBL472152 0.84 CA2 (0.63) CA2CYP1A2CYP2C19HTTHIF1A
SCHEMBL2219412 0.82 CA2 (0.61) CA2CYP1A2CYP2C19HTTHIF1A
SCHEMBL16097557 0.82 CYP1A2 (0.58) CA2CYP1A2CYP2C19HTTHIF1A
Trifluoroacetic Acid SCHEMBL1164011 0.82 CA2 (0.50) CA2CYP1A2CYP2C19HTTHIF1A
SCHEMBL30363570 0.81 EDNRA (0.56) CA2CYP1A2CYP2C19HTTHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2496262-A2 STABILIZED PROTEIN FORMULATIONS AND USE THEREOF Université de Genève (CH) 2012-09-12 EP disclosed
US-20120219538-A1 STABILIZED PROTEIN FORMULATIONS AND USE THEREOF THERAPEOMIC AG (CH) 2012-08-30 US disclosed
WO-2011051916-A2 STABILIZED PROTEIN FORMULATIONS AND USE THEREOF UNIVERSITE DE GENEVE (CH) 2011-05-05 WO disclosed
US-4378500-A LIQUID CHROMATOGRAPHY WITH POLAR SOLVENT VARIAN ASSOCIATES, INC. (US) 1983-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120219538-A1 STABILIZED PROTEIN FORMULATIONS AND USE THEREOF TTR, ALB, CRYZ CA2 4252/4885CYP1A2 4683/4885CYP2C19 4547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.