Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 15/20 | 0.53 |
| ▸ | FABP3 | P05413 | 3/20 | 0.47 |
| ▸ | FABP4 | P15090 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18939322 | 0.87 | APLNR (0.60) | APLNR | |
| SCHEMBL18969643 | 0.85 | APLNR (0.51) | APLNRFABP3FABP4 | |
| SCHEMBL18939540 | 0.85 | APLNR (0.55) | APLNRFABP3FABP4 | |
| SCHEMBL29771940 | 0.85 | APLNR (0.55) | APLNRFABP3FABP4 | |
| SCHEMBL29771934 | 0.82 | APLNR (0.53) | APLNRFABP3FABP4 | |
| SCHEMBL18939307 | 0.82 | APLNR (0.53) | APLNRFABP3FABP4 | |
| SCHEMBL29771942 | 0.82 | APLNR (0.55) | APLNR | |
| SCHEMBL18939402 | 0.82 | APLNR (0.55) | APLNR | |
| SCHEMBL18939425 | 0.79 | RPA1 (0.54) | FABP3FABP4 | |
| SCHEMBL18939591 | 0.79 | APLNR (0.54) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49594-E1 | Apelin receptor (APJ) agonists and uses thereof | RESEARCH TRIANGLE INSTITUTE (US) | 2023-08-01 | — | — | US | disclosed |
| US-20170166577-A1 | APELIN RECEPTOR (APJ) AGONISTS AND USES THEREOF | RESEARCH TRIANGLE INSTITUTE | 2017-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170166577-A1 | APELIN RECEPTOR (APJ) AGONISTS AND USES THEREOF | APLNR, AP1G1, APMAP | APLNR 1/4885FABP3 112/4885FABP4 174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.