Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 12/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | FABP3 | P05413 | 3/20 | 0.44 |
| ▸ | FABP4 | P15090 | 3/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18939220 | 0.88 | APLNR (0.53) | APLNRKMT2AFABP3FABP4FAAH | |
| SCHEMBL29771936 | 0.88 | APLNR (0.53) | APLNRKMT2AFABP3FABP4FAAH | |
| SCHEMBL29771925 | 0.87 | APLNR (0.50) | APLNRFABP3FABP4FAAH | |
| SCHEMBL18939233 | 0.87 | APLNR (0.50) | APLNRFABP3FABP4FAAH | |
| SCHEMBL18969642 | 0.85 | APLNR (0.53) | APLNRFABP3FABP4 | |
| SCHEMBL18939309 | 0.84 | APLNR (0.54) | APLNR | |
| SCHEMBL29771929 | 0.84 | APLNR (0.54) | APLNR | |
| SCHEMBL18969641 | 0.83 | FAAH (0.54) | TDP1FABP3FABP4FAAH | |
| SCHEMBL14800200 | 0.80 | MAPT (0.53) | MAPTKMT2ATDP1FAAH | |
| SCHEMBL18939308 | 0.75 | KMT2A (0.46) | MAPTKMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49594-E1 | Apelin receptor (APJ) agonists and uses thereof | RESEARCH TRIANGLE INSTITUTE (US) | 2023-08-01 | — | — | US | disclosed |
| US-20170166577-A1 | APELIN RECEPTOR (APJ) AGONISTS AND USES THEREOF | RESEARCH TRIANGLE INSTITUTE | 2017-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170166577-A1 | APELIN RECEPTOR (APJ) AGONISTS AND USES THEREOF | APLNR, AP1G1, APMAP | APLNR 1/4885MAPT 4339/4885KMT2A 4000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.