Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 17/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20694580 | 0.84 | LTB4R2 (0.60) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL21097873 | 0.80 | LTB4R2 (0.54) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL21098339 | 0.80 | LTB4R2 (0.54) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL21098639 | 0.78 | LTB4R2 (0.56) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL8344867 | 0.72 | LTB4R2 (0.47) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL18406103 | 0.71 | LTB4R2 (0.60) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL19236573 | 0.71 | LTB4R2 (0.60) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL25964113 | 0.69 | LTB4R2 (0.66) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL19342800 | 0.69 | LTB4R2 (0.63) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL2365 | 0.68 | LTB4R2 (0.80) | LTB4R2AGTR1ABCB11GP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017097275-A1 | SOLID FORMS OF (2R,4S)-5-(BIPHENYL-4-YL)-4-[(3-CARBOXYPROPIONYL)AMINO]-2- -METHYLPENTANOIC ACID ETHYL ESTER, ITS SALTS AND A PREPARATION METHOD | ZENTIVA, K.S. (CZ) | 2017-06-15 | — | — | WO | disclosed |