Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 14/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 8/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8295440 | 0.82 | LTB4R2 (0.61) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL21097873 | 0.76 | LTB4R2 (0.54) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL21098339 | 0.76 | LTB4R2 (0.54) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL29378073 | 0.72 | AGTR1 (0.54) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL18969779 | 0.72 | LTB4R2 (0.48) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL1809623 | 0.72 | AGTR1 (0.54) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL2140 | 0.72 | AGTR1 (0.54) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL8363926 | 0.72 | FFAR1 (0.44) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL19342800 | 0.71 | LTB4R2 (0.63) | LTB4R2AGTR1ABCB11GP6 | |
| SCHEMBL25964104 | 0.71 | AGTR1 (0.67) | LTB4R2AGTR1ABCB11GP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026847-A1 | PROCESS FOR THE MANUFACTURE OF VALSARTAN | NOVARTIS AG (CH) | 2004-04-01 | — | — | WO | disclosed |