Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20368983 | 0.78 | RXFP1 (0.44) | PRNPRXFP1HSD11B1LMNAMAPK1 | |
| SCHEMBL9111915 | 0.78 | RXFP1 (0.53) | PRNPRXFP1HSD11B1LMNAMAPK1 | |
| SCHEMBL21507605 | 0.78 | PRNP (0.53) | PRNPRXFP1HSD11B1LMNAMAPK1 | |
| SCHEMBL24285711 | 0.76 | GPR3 (0.39) | PRNPRXFP1LMNAMAPK1F10 | |
| SCHEMBL2771852 | 0.72 | MAOA (0.50) | MAOBALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16598796 | 0.72 | RXFP1 (0.73) | PRNPRXFP1HSD11B1LMNAMAPK1 | |
| SCHEMBL21708968 | 0.71 | RXFP1 (0.50) | PRNPRXFP1HSD11B1LMNAMAPK1 | |
| SCHEMBL27365531 | 0.71 | RXFP1 (0.47) | PRNPRXFP1HSD11B1LMNAMAPK1 | |
| SCHEMBL2610250 | 0.70 | RXFP1 (0.61) | PRNPRXFP1HSD11B1LMNAMAPK1 | |
| SCHEMBL29939764 | 0.70 | RXFP1 (0.71) | PRNPRXFP1HSD11B1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017100712-A1 | BENZOTHIOPHENE-BASED SELECTIVE ESTROGEN RECEPTOR DOWNREGULATORS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-06-15 | — | — | WO | disclosed |