Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | ACACB | O00763 | 4/20 | 0.34 |
| ▸ | ACACA | Q13085 | 4/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | MST1R | Q04912 | 1/20 | 0.34 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.34 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.34 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18971735 | 1.00 | HSD17B1 (0.36) | HSD17B1SLC6A3ACACBACACAJAK2 | |
| SCHEMBL12115786 | 1.00 | HSD17B1 (0.36) | HSD17B1SLC6A3ACACBACACAJAK2 | |
| SCHEMBL18971220 | 0.91 | JAK2 (0.36) | HSD17B1SLC6A3ACACBACACAJAK2 | |
| SCHEMBL12115754 | 0.91 | JAK2 (0.36) | HSD17B1SLC6A3ACACBACACAJAK2 | |
| SCHEMBL18971151 | 0.89 | HSD17B1 (0.37) | HSD17B1DGAT1MEN1KMT2AESR1 | |
| SCHEMBL12115982 | 0.89 | HSD17B1 (0.37) | HSD17B1DGAT1MEN1KMT2AESR1 | |
| SCHEMBL13285156 | 0.87 | SLC6A3 (0.36) | HSD17B1SLC6A3ACACBACACAJAK2 | |
| SCHEMBL12115776 | 0.87 | SLC6A3 (0.37) | HSD17B1SLC6A3ACACBACACA | |
| SCHEMBL18971232 | 0.87 | SLC6A3 (0.37) | HSD17B1SLC6A3ACACBACACA | |
| SCHEMBL18971635 | 0.87 | SLC6A3 (0.37) | HSD17B1SLC6A3ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155645-B1 | HERBICIDALLY ACTIVE BICYCLIC 1,3-DIONE COMPOUNDS | SYNGENTA LTD (GB) | 2017-06-14 | — | — | EP | disclosed |