Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | EDNRB | P24530 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | MARS1 | P56192 | 3/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12115996 | 1.00 | SLC6A3 (0.37) | SLC6A3EDNRBEDNRAPDK1PDK2 | |
| SCHEMBL12115755 | 0.93 | SLC6A3 (0.41) | SLC6A3EDNRBEDNRAPDK1PDK2 | |
| SCHEMBL18971307 | 0.93 | SLC6A3 (0.41) | SLC6A3EDNRBEDNRAPDK1PDK2 | |
| SCHEMBL18971255 | 0.90 | ABL1 (0.38) | P2RX7 | |
| SCHEMBL12115993 | 0.90 | ABL1 (0.38) | P2RX7 | |
| SCHEMBL12116000 | 0.89 | FASN (0.35) | — | |
| SCHEMBL13284322 | 0.89 | FASN (0.35) | — | |
| SCHEMBL12115773 | 0.88 | ACACB (0.37) | SLC6A3EDNRBEDNRA | |
| SCHEMBL18971321 | 0.88 | ACACB (0.37) | SLC6A3EDNRBEDNRA | |
| SCHEMBL18971733 | 0.84 | EDNRB (0.35) | SLC6A3EDNRBEDNRAPDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155645-B1 | HERBICIDALLY ACTIVE BICYCLIC 1,3-DIONE COMPOUNDS | SYNGENTA LTD (GB) | 2017-06-14 | — | — | EP | disclosed |