Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.34 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | ACACA | Q13085 | 2/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18971255 | 1.00 | ABL1 (0.38) | ABL1P2RX7SUCNR1PTGER4PTGER3 | |
| SCHEMBL18971539 | 0.94 | ABL1 (0.37) | ABL1P2RX7SUCNR1ACACBACACA | |
| SCHEMBL12115876 | 0.94 | ABL1 (0.37) | ABL1P2RX7SUCNR1ACACBACACA | |
| SCHEMBL18971256 | 0.90 | SLC6A3 (0.37) | P2RX7 | |
| SCHEMBL12115996 | 0.90 | SLC6A3 (0.37) | P2RX7 | |
| SCHEMBL12116000 | 0.88 | FASN (0.35) | — | |
| SCHEMBL13284322 | 0.88 | FASN (0.35) | — | |
| SCHEMBL12115773 | 0.87 | ACACB (0.37) | ACACBACACA | |
| SCHEMBL18971321 | 0.87 | ACACB (0.37) | ACACBACACA | |
| SCHEMBL430167 | 0.85 | ABL1 (0.37) | ABL1P2RX7SUCNR1ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155645-B1 | HERBICIDALLY ACTIVE BICYCLIC 1,3-DIONE COMPOUNDS | SYNGENTA LTD (GB) | 2017-06-14 | — | — | EP | disclosed |
| US-8828908-B2 | Herbicidally active bicyclic 1,3-dione compounds | SYNGENTA LIMITED (GB) | 2014-09-09 | — | — | US | disclosed |
| US-8828908-B2 | Herbicidally active bicyclic 1,3-dione compounds | SYNGENTA LIMITED (GB) | 2014-09-09 | — | — | US | disclosed |
| EP-2387311-B1 | BICYCLIC 1,3-DIONES AND THEIR USE AS INSECITICIDES, ACARICIDES AND/OR FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2013-07-10 | — | — | EP | disclosed |
| US-20110275813-A1 | Bicylic 1,3-diones and Their Use as Insecticides, Acaricides and/or Fungicides | BAYER CROPSCIENCE AG (DE) | 2011-11-10 | — | — | US | disclosed |
| US-20110275813-A1 | Bicylic 1,3-diones and Their Use as Insecticides, Acaricides and/or Fungicides | BAYER CROPSCIENCE AG (DE) | 2011-11-10 | — | — | US | disclosed |
| US-20100216638-A1 | HERBICIDALLY ACTIVE BICYCLIC 1,3-DIONE COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-26 | — | — | US | disclosed |
| US-20100216638-A1 | HERBICIDALLY ACTIVE BICYCLIC 1,3-DIONE COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-26 | — | — | US | disclosed |
| WO-2010081686-A1 | BICYCLIC 1,3-DIONES AND THEIR USE AS INSECITICIDES, ACARICIDES AND/OR FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-07-22 | — | — | WO | disclosed |
| WO-2008145336-A1 | HERBICIDALLY ACTIVE BICYCLIC 1,3-DIONE COMPOUNDS | SYNGENTA LIMITED (GB) | 2008-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275813-A1 | Bicylic 1,3-diones and Their Use as Insecticides, Acaricides and/or Fungicides | DDT, CYP1B1, DECR1 | ABL1 1330/4885P2RX7 556/4885SUCNR1 627/4885 |
| US-20100216638-A1 | HERBICIDALLY ACTIVE BICYCLIC 1,3-DIONE COMPOUNDS | DDT, CYP1B1, CYP1A1 | ABL1 1221/4885P2RX7 2728/4885SUCNR1 2205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.