Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | MYLK | Q15746 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12452705 | 0.84 | CA1 (0.36) | KDM4EALDH1A1USP2PDK1PDK2 | |
| SCHEMBL9963779 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1MAPT | |
| SCHEMBL18954349 | 0.83 | KDM4E (0.44) | KDM4EUSP2PDK1PDK2PDK3 | |
| SCHEMBL112067 | 0.82 | CA1 (0.39) | KDM4EALDH1A1USP2PDK1PDK2 | |
| SCHEMBL10115547 | 0.82 | CA1 (0.39) | KDM4EALDH1A1USP2PDK1PDK2 | |
| SCHEMBL110636 | 0.82 | CA1 (0.39) | KDM4EALDH1A1USP2PDK1PDK2 | |
| SCHEMBL19677918 | 0.82 | KDM4E (0.40) | KDM4EALDH1A1USP2PDK1PDK2 | |
| SCHEMBL8370182 | 0.81 | KDM4E (0.42) | KDM4EMAPT | |
| SCHEMBL4589973 | 0.81 | KDM4E (0.42) | KDM4EMAPT | |
| SCHEMBL14477201 | 0.80 | KDM4E (0.41) | KDM4EALDH1A1MAPTCYP3A4NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3475290-B1 | FLUOROCHEMICAL PIPERAZINE CARBOXAMIDES | 3M INNOVATIVE PROPERTIES CO (US) | 2020-08-05 | — | — | EP | disclosed |
| EP-3464252-B1 | FLUOROCHEMICAL PIPERAZINE CARBOXAMIDES | 3M INNOVATIVE PROPERTIES CO (US) | 2020-03-25 | — | — | EP | disclosed |
| WO-2017210006-A1 | FLUOROCHEMICAL PIPERAZINE CARBOXAMIDES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-12-07 | — | — | WO | disclosed |
| WO-2017100045-A1 | FLUORINATED PIPERAZINE SULFONAMIDES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-06-15 | — | — | WO | disclosed |