Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18975057 | 0.89 | KCNH2 (0.40) | KMT2ANR4A2KCNH2KDM4E | |
| SCHEMBL18975224 | 0.88 | KMT2A (0.38) | KMT2AKDM4E | |
| SCHEMBL18975032 | 0.88 | KCNH2 (0.38) | NR4A2KCNH2 | |
| SCHEMBL18975053 | 0.88 | KCNH2 (0.41) | KMT2ANR4A2KCNH2 | |
| SCHEMBL18975021 | 0.86 | KCNH2 (0.34) | NR4A2KCNH2KDM4E | |
| SCHEMBL18975208 | 0.85 | KMT2A (0.36) | KMT2A | |
| SCHEMBL18974973 | 0.84 | NR4A2 (0.41) | KMT2ANR4A2KCNH2 | |
| SCHEMBL18975231 | 0.81 | JAK3 (0.38) | — | |
| SCHEMBL18975226 | 0.81 | MAPT (0.36) | KMT2ANR4A2 | |
| SCHEMBL18974960 | 0.81 | RAB9A (0.41) | KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170166561-A1 | QUINUCLIDINE COMPOUNDS FOR MODULATING ALPHA7-NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVITY | ALPHARMAGEN LLC (US) | 2017-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170166561-A1 | QUINUCLIDINE COMPOUNDS FOR MODULATING ALPHA7-NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVITY | CHRNA7, CHRNA2, CHRNA6 | KMT2A 2566/4885NR4A2 358/4885KCNH2 487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.