Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22450554 | 0.92 | PADI4 (0.54) | PADI4 | |
| SCHEMBL22450519 | 0.90 | PADI4 (0.61) | PADI4 | |
| SCHEMBL18960699 | 0.90 | PADI4 (0.74) | PADI4 | |
| SCHEMBL18975351 | 0.89 | PADI4 (0.56) | PADI4 | |
| SCHEMBL23436021 | 0.89 | PADI4 (0.64) | PADI4 | |
| SCHEMBL18938868 | 0.88 | PADI4 (0.54) | PADI4 | |
| SCHEMBL22450587 | 0.86 | PADI4 (0.49) | PADI4 | |
| SCHEMBL18938867 | 0.86 | PADI4 (0.56) | PADI4 | |
| SCHEMBL23435380 | 0.85 | PADI4 (0.72) | PADI4 | |
| SCHEMBL18955611 | 0.85 | PADI4 (0.59) | PADI4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017100601-A1 | AZA-BENZIMIDAZOLE INHIBITORS OF PAD4 | PADLOCK THERAPEUTICS, INC. (US) | 2017-06-15 | — | — | WO | disclosed |