Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12566558 | 0.79 | PTPN1 (0.36) | KMT2AMAPTMEN1PTPN1CYP1A2 | |
| SCHEMBL23809439 | 0.77 | ACE2 (0.49) | KDM4EKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL13806232 | 0.75 | MMP2 (0.44) | KDM4EPOLBALDH1A1ALOX15CDC25B | |
| SCHEMBL22408117 | 0.73 | JAK2 (0.31) | PTPN1 | |
| SCHEMBL25143702 | 0.72 | PTPN1 (0.45) | KDM4EKMT2AMAPTMEN1THRB | |
| SCHEMBL14977223 | 0.71 | F2RL1 (0.35) | KMT2AMAPTMEN1USP2KEAP1 | |
| SCHEMBL23809437 | 0.70 | ACE2 (0.49) | KDM4EKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL14886437 | 0.70 | MAPT (0.46) | KDM4EMAPTTDP1POLBALDH1A1 | |
| SCHEMBL5138289 | 0.70 | KDM4E (0.53) | KDM4EKMT2AMAPTALDH1A1PTPN1 | |
| SCHEMBL14051377 | 0.70 | KDM4E (0.36) | KDM4EKMT2ATDP1PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651516-B1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'ORÉAL (FR) | 2017-06-14 | — | — | EP | disclosed |