Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | AKT1 | P31749 | 2/20 | 0.67 |
| ▸ | ESR1 | P03372 | 1/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.67 |
| ▸ | CDC25A | P30304 | 1/20 | 0.67 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | PRKCG | P05129 | 1/20 | 0.49 |
| ▸ | PRKCB | P05771 | 1/20 | 0.49 |
| ▸ | PRKCA | P17252 | 1/20 | 0.49 |
| ▸ | PRKCH | P24723 | 1/20 | 0.49 |
| ▸ | PRKCI | P41743 | 1/20 | 0.49 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.49 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.49 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.49 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28738156 | 0.87 | LMNA (0.56) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL4972574 | 0.87 | LMNA (0.86) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL11994572 | 0.84 | LMNA (0.46) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL8738432 | 0.84 | LMNA (0.46) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL29465558 | 0.80 | LMNA (1.00) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL10415264 | 0.80 | LMNA (1.00) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL596694 | 0.80 | LMNA (1.00) | LMNAAKT1ESR1ADORA3CDC25A | |
| Miltefosine SCHEMBL20769827 | 0.80 | LMNA (1.00) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL21437276 | 0.80 | LMNA (0.56) | LMNAAKT1ESR1ADORA3CDC25A | |
| Octadecylphosphonocholine SCHEMBL744376 | 0.80 | LMNA (1.00) | LMNAAKT1ESR1ADORA3CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940907-B2 | Synthesis of phosphoric esters | MERCK PATENT GMBH (DE) | 2015-01-27 | — | — | US | disclosed |
| EP-2496586-B1 | SYNTHESIS OF PHOSPHORIC ESTERS | MERCK PATENT GMBH (DE) | 2013-12-18 | — | — | EP | disclosed |
| EP-2496586-A1 | SYNTHESIS OF PHOSPHORIC ESTERS | Merck Patent GmbH (DE) | 2012-09-12 | — | — | EP | disclosed |
| US-20120215006-A1 | SYNTHESIS OF PHOSPHORIC ESTERS | MERCK PATENTS GESSELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-08-23 | — | — | US | disclosed |
| WO-2011054429-A1 | SYNTHESIS OF PHOSPHORIC ESTERS | MERCK PATENT GMBH (DE) | 2011-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120215006-A1 | SYNTHESIS OF PHOSPHORIC ESTERS | PPIP5K2, PHOSPHO1, PPA1 | LMNA 3173/4885AKT1 1024/4885ESR1 322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.