⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL140519 | 0.85 | LPL (0.32) | — | |
| SCHEMBL18975580 | 0.76 | — | — | |
| SCHEMBL18898350 | 0.72 | LPL (0.30) | — | |
| SCHEMBL19523853 | 0.72 | UCHL1 (0.31) | — | |
| SCHEMBL21382126 | 0.71 | LPL (0.34) | — | |
| SCHEMBL21583422 | 0.71 | LPL (0.35) | — | |
| SCHEMBL18389226 | 0.71 | LPL (0.35) | — | |
| SCHEMBL20543216 | 0.69 | FFAR1 (0.33) | — | |
| SCHEMBL20516993 | 0.69 | LPL (0.30) | — | |
| SCHEMBL23064189 | 0.69 | LPL (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017097224-A1 | AZETIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2017-06-15 | — | — | WO | disclosed |