Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.46 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.46 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18975988 | 0.88 | HRH4 (0.47) | RAB9AALDH1A1NPC1MAPTSMN1; SMN2 | |
| SCHEMBL18975812 | 0.86 | RAB9A (0.56) | RAB9AALDH1A1NPC1MAPTSMN1; SMN2 | |
| SCHEMBL20580855 | 0.77 | RAB9A (0.50) | RAB9AALDH1A1NPC1MAPTSMN1; SMN2 | |
| SCHEMBL14320471 | 0.75 | RAB9A (0.72) | RAB9AALDH1A1NPC1MAPTSMN1; SMN2 | |
| SCHEMBL19864572 | 0.74 | ALDH1A1 (1.00) | RAB9AALDH1A1NPC1MAPTSMN1; SMN2 | |
| SCHEMBL15170873 | 0.74 | ALDH1A1 (1.00) | RAB9AALDH1A1NPC1MAPTSMN1; SMN2 | |
| SCHEMBL10259970 | 0.73 | RAB9A (0.63) | RAB9AALDH1A1NPC1MAPTSMN1; SMN2 | |
| SCHEMBL8277152 | 0.73 | RAB9A (0.63) | RAB9AALDH1A1NPC1MAPTSMN1; SMN2 | |
| SCHEMBL8276746 | 0.73 | RAB9A (0.63) | RAB9AALDH1A1NPC1MAPTSMN1; SMN2 | |
| SCHEMBL18976462 | 0.73 | NPC1 (0.45) | RAB9AALDH1A1NPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017098257-A1 | PBD ANTIBACTERIAL AGENTS | KING'S COLLEGE LONDON (GB) | 2017-06-15 | — | — | WO | disclosed |