Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18975997 | 0.87 | SIRT1 (0.35) | BTKSIRT1 | |
| SCHEMBL18976057 | 0.86 | BTK (0.47) | BTKSIRT1 | |
| SCHEMBL16320601 | 0.76 | BTK (0.39) | BTK | |
| SCHEMBL16320561 | 0.76 | BTK (0.47) | BTKSIRT1 | |
| SCHEMBL19279359 | 0.73 | BTK (0.54) | BTKSIRT1 | |
| SCHEMBL19279261 | 0.72 | BTK (0.47) | BTKSIRT1 | |
| SCHEMBL19715422 | 0.72 | BTK (0.58) | BTKSIRT1 | |
| SCHEMBL16339727 | 0.69 | TP53 (0.38) | BTKSIRT1 | |
| SCHEMBL18976004 | 0.69 | SIRT1 (0.31) | SIRT1 | |
| SCHEMBL19715301 | 0.67 | BTK (0.56) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013814-B1 | SUBSTITUTED TETRAHYDROCARBAZOLE AND CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-06-14 | — | — | EP | disclosed |