Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.52 |
| ▸ | EBP | Q15125 | 3/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anipamil SCHEMBL247837 | 0.84 | SIGMAR1 (0.69) | SIGMAR1EBPABCB1CYP3A4ABCC1 | |
| Anipamil SCHEMBL31479919 | 0.84 | SIGMAR1 (0.69) | SIGMAR1EBPABCB1CYP3A4ABCC1 | |
| Anipamil SCHEMBL7199272 | 0.84 | SIGMAR1 (0.67) | SIGMAR1EBPABCB1CYP3A4ABCC1 | |
| Anipamil SCHEMBL9177433 | 0.84 | SIGMAR1 (0.67) | SIGMAR1EBPABCB1CYP3A4ABCC1 | |
| SCHEMBL24224796 | 0.77 | SIGMAR1 (0.60) | SIGMAR1EBPABCB1CYP3A4ABCC1 | |
| Dagapamil SCHEMBL2110079 | 0.76 | SIGMAR1 (0.60) | SIGMAR1EBPABCB1CYP3A4ABCC1 | |
| Ronipamil SCHEMBL1814126 | 0.71 | SIGMAR1 (1.00) | SIGMAR1EBPKCNH2SLC6A4CHRM2 | |
| SCHEMBL7322417 | 0.70 | CHRM2 (0.46) | SIGMAR1EBPABCB1CYP3A4MEN1 | |
| SCHEMBL9490822 | 0.69 | SIGMAR1 (0.53) | SIGMAR1EBPABCB1CYP3A4ABCC1 | |
| Anipamil SCHEMBL741478 | 0.68 | SCN1A (0.62) | SIGMAR1EBPABCB1CYP3A4ABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011060944-A2 | ACTIVE PHARMACEUTICAL INGREDIENT CAPSULES AND POLYUNSATURATED FATTY ACID ESTERS | GP PHARM, S.A. (ES) | 2011-05-26 | — | — | WO | claimed |