SCHEMBL1897682

SCHEMBL1897682

Cc1cccc(NCCCS(=O)(=O)O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.61
CYP1A2 P05177 1/20 0.61
CYP3A4 P08684 1/20 0.61
CYP2D6 P10635 1/20 0.61
CYP2C9 P11712 1/20 0.61
CYP2C19 P33261 1/20 0.61
HTT P42858 1/20 0.61
GFER P55789 1/20 0.44
ALDH1A1 P00352 2/20 0.44
HDAC1 Q13547 2/20 0.44
HPGD P15428 1/20 0.44
GAA P10253 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MAPK1 P28482 1/20 0.44
CASP6 P55212 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
HSD17B10 Q99714 1/20 0.44
FBP1 P09467 5/20 0.43
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9551536 0.98 MAPT (0.59) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL4940220 0.97 MAPT (0.61) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL1257436 0.95 MAPT (0.59) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL8969909 0.95 MAPT (0.59) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL10642878 0.90 MAPT (0.65) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL1823998 0.83 THRB (0.44) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL9551534 0.83 MAPT (0.59) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL4863177 0.83 MAPT (0.59) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL11475109 0.83 HTR7 (0.49) MAPTCYP1A2CYP3A4HTTALDH1A1
SCHEMBL10795105 0.83 MEN1 (0.46) MAPTHTTALDH1A1L3MBTL1FBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105652021-B A kind of reagent, method and kit for determining small and dense lipoprotein 上海练佰生物技术中心 2018-01-02 CN claimed
EP-3801036-A1 USE OF HEXOSE OXIDASE AND/OR CELLOBIOSE OXIDASE FOR REDUCTION OF MAILLARD REACTION Chr. Hansen A/S (DK) 2021-04-14 EP disclosed
EP-2203181-B1 AN ORALLY ADMINISTERABLE SOLID PHARMACEUTICAL COMPOSITION AND A PROCESS THEREOF BIOCON LTD (IN) 2018-02-14 EP disclosed
CN-105699640-B A kind of kit for detecting gut barrier function 北京中生金域诊断技术股份有限公司 2017-06-06 CN disclosed
CN-104076158-B A kind of test kit for measuring HDL-C 深圳市新产业生物医学工程股份有限公司 2016-08-17 CN disclosed
US-9241908-B2 Orally administrable solid pharmaceutical composition and a process thereof BIOCON LIMITED (IN) 2016-01-26 US disclosed
EP-2499227-A1 A BREWING METHOD Novozymes A/S (DK) 2012-09-19 EP disclosed
EP-2456865-A1 CARBOHYDRATE OXIDASES Novozymes A/S (DK) 2012-05-30 EP disclosed
WO-2011133581-A1 METHODS AND COMPOSITIONS FOR ASSAYING ENZYMATIC ACTIVITY OF MYELOPEROXIDASE IN BLOOD SAMPLES GENERAL ATOMICS (US) 2011-10-27 WO disclosed
WO-2011058105-A1 A BREWING METHOD NOVOZYMES A/S (DK) 2011-05-19 WO disclosed
WO-2011009747-A1 CARBOHYDRATE OXIDASES NOVOZYMES A/S (DK) 2011-01-27 WO disclosed
US-20100285143-A1 ORALLY ADMINISTERABLE SOLID PHARMACEUTICAL COMPOSITION AND A PROCESS THEREOF BIOCON LIMITED (IN) 2010-11-11 US disclosed
EP-2203181-A2 AN ORALLY ADMINISTERABLE SOLID PHARMACEUTICAL COMPOSITION AND A PROCESS THEREOF Biocon Limited (IN) 2010-07-07 EP disclosed
EP-1677665-A4 DETERMINATION OF IONS USING ION-SENSITIVE ENZYMES GEN ATOMICS (US) 2009-07-01 EP disclosed
WO-2009050738-A2 AN ORALLY ADMINISTERABLE SOLID PHARMACEUTICAL COMPOSITION AND A PROCESS THEREOF BIOCON LIMITED (IN) 2009-04-23 WO disclosed
EP-1677665-A2 DETERMINATION OF IONS USING ION-SENSITIVE ENZYMES GENERAL ATOMICS (US) 2006-07-12 EP disclosed
CN-1620501-A Polypeptides having cellobiohydrolase i activity and polynucleotides encoding same NOVOZYMES AS (DK) 2005-05-25 CN disclosed
WO-2005027725-A2 DETERMINATION OF IONS USING ION-SENSITIVE ENZYMES GENERAL ATOMICS (US) 2005-03-31 WO disclosed
EP-1380642-A1 A method for the separation and purification of nucleic acid FUJI PHOTO FILM CO., LTD. (JP) 2004-01-14 EP disclosed