Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 2/20 | 0.50 |
| ▸ | ATP4B | P51164 | 2/20 | 0.50 |
| ▸ | HTR7 | P34969 | 5/20 | 0.42 |
| ▸ | DHODH | Q02127 | 6/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28534560 | 0.87 | HTR7 (0.43) | ATP4AATP4BHTR7DHODHHSP90AA1 | |
| SCHEMBL30849483 | 0.81 | DHODH (0.53) | ATP4AATP4BDHODHHSP90AA1HSP90AB1 | |
| SCHEMBL22552455 | 0.81 | DHODH (0.53) | ATP4AATP4BDHODHHSP90AA1HSP90AB1 | |
| SCHEMBL8170195 | 0.80 | ATP4A (0.48) | ATP4AATP4BHTR7ALKBH5FTO | |
| SCHEMBL28524081 | 0.80 | IDO1 (0.46) | ATP4AATP4BHTR7ALKBH5FTO | |
| SCHEMBL13430732 | 0.77 | KCNH2 (0.48) | ATP4AATP4BHTR7SLC22A12ALDH1A1 | |
| SCHEMBL13430763 | 0.75 | KCNH2 (0.47) | ATP4AATP4BDHODHALDH1A1 | |
| SCHEMBL28223492 | 0.75 | HTR2A (0.36) | ATP4AATP4BHTR7HSP90AA1HSP90AB1 | |
| SCHEMBL13430762 | 0.75 | TSHR (0.43) | HTR7ALDH1A1TSHR | |
| SCHEMBL13430733 | 0.75 | KCNH2 (0.46) | ATP4AATP4BHTR7SLC22A12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2812001-B1 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2017-06-14 | — | — | EP | disclosed |