Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 16/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.40 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MAP3K2 | Q9Y2U5 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18976977 | 0.91 | AOC3 (0.54) | AOC3KCNH2 | |
| SCHEMBL20924441 | 0.86 | AOC3 (0.57) | AOC3CYP1A2TGFBR1KCNH2 | |
| SCHEMBL18976723 | 0.85 | AOC3 (0.68) | AOC3KCNH2 | |
| SCHEMBL20924378 | 0.82 | AOC3 (0.75) | AOC3KCNH2 | |
| SCHEMBL18976721 | 0.82 | AOC3 (0.66) | AOC3KCNH2 | |
| SCHEMBL18976983 | 0.81 | AOC3 (0.61) | AOC3KCNH2 | |
| SCHEMBL20924505 | 0.80 | AOC3 (0.64) | AOC3KCNH2 | |
| SCHEMBL20924435 | 0.77 | KCNH2 (0.60) | AOC3KCNH2 | |
| SCHEMBL16053333 | 0.76 | AOC3 (0.75) | AOC3KCNH2 | |
| SCHEMBL20924446 | 0.74 | AOC3 (0.59) | AOC3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970260-B1 | IMIDAZO[4,5-C]PYRIDINE AND PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS SSAO INHIBITORS | PROXIMAGEN LLC (US) | 2019-04-24 | — | — | EP | disclosed |