Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.39 |
| ▸ | SLC2A2 | P11168 | 10/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1691779 | 0.89 | DPP4 (0.49) | SLC2A1SLC2A2DPP4 | |
| SCHEMBL1691330 | 0.79 | DPP4 (0.50) | SLC2A1SLC2A2DPP4KDM4ELMNA | |
| SCHEMBL1691857 | 0.78 | TGFBR1 (0.41) | CDK2SLC2A2GABRA1GABRB2CDK4 | |
| SCHEMBL1691484 | 0.77 | SLC2A1 (0.60) | SLC2A1SLC2A2ALBOPRK1GABRA2 | |
| SCHEMBL1691129 | 0.74 | SLC2A1 (0.47) | SLC2A1KDM4ELMNAALBCYP3A4 | |
| SCHEMBL1691422 | 0.74 | DPP4 (0.54) | SLC2A1SLC2A2DPP4GABRA2GABRB2 | |
| SCHEMBL1691704 | 0.72 | GABRA1 (0.54) | SLC2A1KDM4ELMNAALBCYP3A4 | |
| SCHEMBL1691850 | 0.72 | DPP4 (0.50) | SLC2A1SLC2A2DPP4 | |
| SCHEMBL1691693 | 0.72 | SLC2A1 (0.45) | CDK2SLC2A1KDM4ELMNAALB | |
| SCHEMBL1691367 | 0.71 | SLC2A1 (0.52) | SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017098236-A1 | VAP-1 INHIBITORS FOR TREATING PAIN | PROXIMAGEN LIMITED (GB) | 2017-06-15 | — | — | WO | disclosed |