Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.39 |
| ▸ | C1S | P09871 | 2/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1738243 | 0.82 | F10 (0.42) | DAOPRSS1PRSS2PRSS3C1S | |
| Hydrochloric Acid SCHEMBL1467818 | 0.80 | LOXL2 (0.41) | DAOPRSS1PRSS2PRSS3C1S | |
| Hydrochloric Acid SCHEMBL22468237 | 0.80 | LOXL2 (0.41) | DAOPRSS1PRSS2PRSS3C1S | |
| SCHEMBL10163846 | 0.80 | DAO (0.69) | DAORAB9ATP53USP2GAA | |
| SCHEMBL25364134 | 0.79 | DAO (0.37) | DAORAB9ATP53USP2PRSS1 | |
| SCHEMBL25363680 | 0.78 | DAO (0.38) | DAOPRSS1PRSS2PRSS3C1S | |
| SCHEMBL15145113 | 0.77 | PRSS1 (0.36) | DAOPRSS1PRSS2PRSS3C1S | |
| SCHEMBL25364308 | 0.77 | ITGB3 (0.36) | DAOPRSS1PRSS2PRSS3TMPRSS15 | |
| Hydrochloric Acid SCHEMBL26119846 | 0.77 | DAO (0.37) | DAOPRSS1PRSS3TMPRSS15 | |
| SCHEMBL26579403 | 0.77 | PRSS1 (0.44) | DAOPRSS1PRSS2PRSS3C1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183405-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |
| WO-2017096472-A1 | CEPHEM COMPOUNDS, THEIR PRODUCTION AND USE | NAEJA-RGM PHARMACEUTICALS INC. (CA) | 2017-06-15 | — | — | WO | disclosed |