Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 6/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | MET | P08581 | 2/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18939091 | 0.82 | RPS6KA5 (0.41) | GRIN2BCYP1A2CYP2C9CYP2C19GRIN1 | |
| SCHEMBL18960813 | 0.81 | SLC22A12 (0.38) | GRIN2BNR3C1NR3C2CYP1A2CYP2C9 | |
| SCHEMBL18939015 | 0.81 | PLAU (0.41) | GRIN2BNR3C1NR3C2RPS6KA5MET | |
| Hydrochloric Acid SCHEMBL18938985 | 0.80 | SLC22A12 (0.37) | GRIN2BNR3C1NR3C2CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL18939169 | 0.80 | SLC22A12 (0.45) | GRIN2BRPS6KA5METSLC22A12 | |
| SCHEMBL18939149 | 0.78 | MET (0.40) | GRIN2BMEN1MAPK1KMT2ANR3C1 | |
| SCHEMBL28662877 | 0.76 | CYP19A1 (0.43) | GRIN2BNR3C1RAPGEF4SLC22A12 | |
| SCHEMBL28651087 | 0.76 | KDR (0.51) | GRIN2BCYP1A2CYP2C9RAPGEF4SLC22A12 | |
| SCHEMBL18967497 | 0.75 | SLC22A12 (0.36) | GRIN2BMEN1KMT2ARPS6KA5MET | |
| SCHEMBL18967605 | 0.74 | HDAC10 (0.39) | MAPK1NR3C1NR3C2SLC22A12PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108463461-B | Cephem compounds, their preparation and use | 奈加-RGM制药有限公司 | 2021-11-19 | — | — | CN | disclosed |
| WO-2017096472-A1 | CEPHEM COMPOUNDS, THEIR PRODUCTION AND USE | NAEJA-RGM PHARMACEUTICALS INC. (CA) | 2017-06-15 | — | — | WO | disclosed |