Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30537273 | 1.00 | EPHX1 (0.42) | EPHX1TRPM8TRPA1LMNAMAPT | |
| SCHEMBL21328419 | 0.83 | EPHX1 (0.40) | EPHX1TRPM8TRPA1LMNAMAPT | |
| SCHEMBL1030881 | 0.79 | EPHX1 (0.44) | EPHX1TRPM8TRPA1LMNAMAPT | |
| SCHEMBL28738013 | 0.79 | TRPM8 (0.47) | EPHX1TRPM8TRPA1LMNAMAPT | |
| SCHEMBL114684 | 0.77 | EPHX1 (0.44) | EPHX1TRPM8TRPA1CYP19A1ALDH1A1 | |
| SCHEMBL29243148 | 0.76 | EPHX1 (0.46) | EPHX1TRPM8TRPA1CYP19A1ALDH1A1 | |
| SCHEMBL18911277 | 0.75 | EPHX1 (0.40) | EPHX1TRPM8TRPA1LMNAMAPT | |
| Bicarbonate SCHEMBL1660906 | 0.74 | EPHX1 (0.47) | EPHX1TRPM8TRPA1LMNACYP19A1 | |
| SCHEMBL31148535 | 0.73 | TRPM8 (0.52) | EPHX1TRPM8TRPA1LMNACYP19A1 | |
| SCHEMBL21380224 | 0.71 | TRPM8 (0.45) | EPHX1TRPM8TRPA1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056759-A2 | ORAL COMPOSITIONS FOR TREATMENT OF DRY MOUTH | THE PROCTER & GAMBLE COMPANY (US) | 2011-05-12 | — | — | WO | disclosed |