Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18978357 | 0.94 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18978592 | 0.89 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21895729 | 0.89 | SRC (0.57) | ALDH1A1L3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1581485 | 0.89 | SRC (0.57) | ALDH1A1L3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18978610 | 0.88 | ELANE (0.56) | ALDH1A1L3MBTL1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18978367 | 0.85 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18978368 | 0.84 | HCAR2 (0.55) | ALDH1A1CYP3A4SRCMEN1KMT2A | |
| SCHEMBL18978238 | 0.81 | RAB9A (0.43) | ALDH1A1L3MBTL1CYP2C9SRCMAPT | |
| SCHEMBL11526737 | 0.81 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1CYP3A4SRCKMT2A | |
| SCHEMBL18978440 | 0.80 | TP53 (0.46) | ALDH1A1L3MBTL1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017097870-A1 | SUBSTITUTED MALONIC ACID AMIDES AS INSECTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-06-15 | — | — | WO | disclosed |