Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18978225 | 0.83 | SRC (0.41) | SRCTSHRALDH1A1TDP1KMT2A | |
| SCHEMBL18978232 | 0.82 | ALDH1A1 (0.40) | SRCTSHRALDH1A1TDP1KMT2A | |
| SCHEMBL18978356 | 0.79 | SRC (0.35) | SRCALDH1A1TDP1KMT2AMMP8 | |
| SCHEMBL8965019 | 0.78 | KLK7 (0.46) | TSHRALDH1A1TDP1LMNAHTT | |
| SCHEMBL18978602 | 0.77 | SRC (0.36) | SRCTSHRALDH1A1TDP1KMT2A | |
| SCHEMBL5320869 | 0.76 | LMNA (0.47) | TSHRALDH1A1TDP1KMT2ASMN1; SMN2 | |
| SCHEMBL11505425 | 0.76 | KMT2A (0.42) | TSHRALDH1A1TDP1KMT2ASMN1; SMN2 | |
| SCHEMBL5932426 | 0.74 | TSHR (0.45) | SRCTSHRALDH1A1TDP1KMT2A | |
| SCHEMBL18978228 | 0.73 | SRC (0.38) | SRCALDH1A1TDP1KMT2AMMP8 | |
| SCHEMBL11022227 | 0.73 | KMT2A (0.46) | TSHRALDH1A1TDP1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017097870-A1 | SUBSTITUTED MALONIC ACID AMIDES AS INSECTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-06-15 | — | — | WO | disclosed |