Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3754005 | 0.86 | TDP1 (0.48) | TDP1MEN1KMT2AATMGAA | |
| SCHEMBL9931542 | 0.86 | TDP1 (0.48) | TDP1MEN1KMT2AATMGAA | |
| SCHEMBL29400712 | 0.86 | TDP1 (0.48) | TDP1MEN1KMT2AATMGAA | |
| SCHEMBL21901505 | 0.86 | MEN1 (0.44) | TDP1MEN1KMT2AATMGAA | |
| SCHEMBL18206800 | 0.85 | CA1 (0.49) | TDP1MEN1KMT2AATMGAA | |
| SCHEMBL18206801 | 0.85 | CA1 (0.49) | TDP1MEN1KMT2AATMGAA | |
| SCHEMBL30895563 | 0.83 | MEN1 (0.48) | TDP1MEN1KMT2AATMGAA | |
| SCHEMBL12604209 | 0.83 | MEN1 (0.48) | TDP1MEN1KMT2AATMGAA | |
| SCHEMBL18221182 | 0.82 | MEN1 (0.46) | TDP1MEN1KMT2AATMGAA | |
| SCHEMBL17227817 | 0.82 | MEN1 (0.46) | TDP1MEN1KMT2AATMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017098533-A2 | PROCESS FOR PREPARATION OF LISDEXAMPHETAMINE | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2017-06-15 | — | — | WO | disclosed |