Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9931542 | 0.91 | TDP1 (0.48) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL3754005 | 0.91 | TDP1 (0.48) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL29400712 | 0.91 | TDP1 (0.48) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL18206800 | 0.90 | CA1 (0.49) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL18206801 | 0.90 | CA1 (0.49) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL30895563 | 0.87 | MEN1 (0.48) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL12604209 | 0.87 | MEN1 (0.48) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL18978667 | 0.86 | TDP1 (0.40) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL18221182 | 0.86 | MEN1 (0.46) | MEN1KMT2AGAATDP1ATM | |
| SCHEMBL17227817 | 0.86 | MEN1 (0.46) | MEN1KMT2AGAATDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081744-A1 | IMMUNOMODULATING POLYNUCLEOTIDE CONJUGATES AND METHODS OF USE | TOLLNINE, INC. (US) | 2020-04-23 | — | — | WO | disclosed |