SCHEMBL30895563

SCHEMBL30895563

CC(C)(C)OC(=O)NCCC[C@H](NC(=O)OC(C)(C)C)C(=O)ON1C(=O)CCC1=O

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.48
▸ KMT2A Q03164 3/20 0.48
▸ GAA P10253 1/20 0.48
▸ TDP1 Q9NUW8 7/20 0.44
▸ ATM Q13315 2/20 0.44
▸ KLK7 P49862 1/20 0.42
▸ KLK5 Q9Y337 1/20 0.42
▸ POLB P06746 4/20 0.42
▸ NPSR1 Q6W5P4 3/20 0.42
▸ MAPT P10636 1/20 0.41
▸ CTSK P43235 3/20 0.40
▸ CTSS P25774 1/20 0.40
▸ CA1 P00915 2/20 0.40
▸ CA2 P00918 2/20 0.40
▸ ACE P12821 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12604209 1.00 MEN1 (0.48) MEN1KMT2AGAATDP1ATM
SCHEMBL3754005 0.97 TDP1 (0.48) MEN1KMT2AGAATDP1ATM
SCHEMBL29400712 0.97 TDP1 (0.48) MEN1KMT2AGAATDP1ATM
SCHEMBL9931542 0.97 TDP1 (0.48) MEN1KMT2AGAATDP1ATM
SCHEMBL16076756 0.93 MEN1 (0.49) MEN1KMT2AGAATDP1ATM
SCHEMBL10190377 0.92 MEN1 (0.40) MEN1KMT2AGAATDP1ATM
SCHEMBL18206800 0.91 CA1 (0.49) MEN1KMT2AGAATDP1ATM
SCHEMBL18206801 0.91 CA1 (0.49) MEN1KMT2AGAATDP1ATM
SCHEMBL10046236 0.90 MEN1 (0.38) MEN1KMT2AGAATDP1ATM
SCHEMBL15893373 0.89 TDP1 (0.44) MEN1KMT2AGAATDP1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260083853-A1 CD70 ANTIBODY DRUG CONJUGATES AND METHODS OF USING THE SAME GENMAB AS (DK) 2026-03-26 — — US disclosed
EP-4608451-A1 CD70 ANTIBODY DRUG CONJUGATES AND METHODS OF USING THE SAME Genmab A/S (DK) 2025-09-03 — — EP disclosed
US-20240261427-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PROFOUNDBIO US CO. 2024-08-08 — — US disclosed
US-20240245796-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PROFOUNDBIO US CO. 2024-07-25 — — US disclosed
US-20240207429-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME WILMINGTON TRUST, NATIONAL ASSOCIATION 2024-06-27 — — US disclosed
US-20240207418-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PROFOUNDBIO US CO. 2024-06-27 — — US disclosed
WO-2024092067-A1 CD70 ANTIBODY DRUG CONJUGATES AND METHODS OF USING THE SAME PROFOUNDBIO US CO. (US) 2024-05-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083853-A1 CD70 ANTIBODY DRUG CONJUGATES AND METHODS OF USING THE SAME CD74, HACD3, FCGR2A MEN1 3457/4885KMT2A 2327/4885GAA 3500/4885
US-20240207418-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PAICS, DHFR, CD44 MEN1 1967/4885KMT2A 2447/4885GAA 1776/4885
US-20240207429-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PAICS, DHFR, CD44 MEN1 1967/4885KMT2A 2447/4885GAA 1776/4885
US-20240261427-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PAICS, DHFR, CD44 MEN1 1967/4885KMT2A 2447/4885GAA 1776/4885
US-20240245796-A1 LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME PAICS, DHFR, CD44 MEN1 1967/4885KMT2A 2447/4885GAA 1776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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