SCHEMBL1897902

SCHEMBL1897902

CC(=O)CC(=O)SN1C(=O)CCC1=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 5/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11568571 0.79 LMNA (0.31)
SCHEMBL5929267 0.76 GLA (0.33)
SCHEMBL733348 0.67
SCHEMBL1269711 0.67
Acetoacetic Acid SCHEMBL28926068 0.65 EGLN1 (0.35) TLR4ALDH1A1MAPT
SCHEMBL6033533 0.64 MGAM (0.43) TLR4ALDH1A1MAPT
SCHEMBL5091798 0.63 TSHR (0.44) ALDH1A1
Propionic Acid SCHEMBL2689338 0.63 FFAR3 (0.43) ALDH1A1
SCHEMBL5088057 0.62 TSHR (0.37) ALDH1A1MAPT
SCHEMBL24287571 0.61 SMN1; SMN2 (0.46) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118217402-A Combination therapy for C3 inhibition 阿佩利斯制药有限公司 2024-06-21 CN disclosed
CN-117503905-A dosing regimen 阿佩利斯制药有限公司 2024-02-06 CN disclosed
CN-110882376-B Cell-reactive, long-acting or targeted compstatin analogs and related compositions and methods 阿佩利斯制药公司 2023-10-20 CN disclosed
CN-116059313-A Dosing regimen and related compositions and methods 阿佩利斯制药有限公司 2023-05-05 CN disclosed
CN-115135680-A Mass cytometry reagents and methods for signal amplification 标准生物工具加拿大公司 2022-09-30 CN disclosed
CN-109562152-A Drug conjugate containing the autostability connector with improved physiochemical properties 西雅图基因公司 2019-04-02 CN disclosed
EP-3083979-B1 CELL DETECTION, CAPTURE AND ISOLATION METHODS AND APPARATUS AXON DX LLC (US) 2019-02-20 EP disclosed
US-10147180-B2 Cell detection, capture and isolation methods and apparatus AXON DX, LLC (US) 2018-12-04 US disclosed
US-20160314583-A1 CELL DETECTION, CAPTURE AND ISOLATION METHODS AND APPARATUS AXON DX, LLC 2016-10-27 US disclosed
EP-3083979-A1 CELL DETECTION, CAPTURE AND ISOLATION METHODS AND APPARATUS Axon DX, LLC (US) 2016-10-26 EP disclosed
EP-2325641-A1 Biological indicator American Sterilizer Company (US) 2011-05-25 EP disclosed
US-7741107-B2 Biological indicator AMERICAN STERILIZER COMPANY (US) 2010-06-22 US disclosed
US-20100151562-A1 Biological indicator AMERICAN STERILIZER COMPANY (US) 2010-06-17 US disclosed
US-20100151563-A1 Biological indicator AMERICAN STERILIZER COMPANY (US) 2010-06-17 US disclosed
US-20100143930-A1 Biological indicator AMERICAN STERILIZER COMPANY (US) 2010-06-10 US disclosed
US-7416883-B2 Biological indicator STERIS INC. (US) 2008-08-26 US disclosed
US-20080199903-A1 Biological indicator STERIS INC. (US) 2008-08-21 US disclosed
EP-1886143-A1 BIOLOGICAL INDICATOR Steris, Inc. (US) 2008-02-13 EP disclosed
WO-2007046865-A1 BIOLOGICAL INDICATOR STERIS, INC. (US) 2007-04-26 WO disclosed
US-20060269983-A1 Biological indicator AMERICAN STERILIZER COMPANY 2006-11-30 US disclosed