Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL121100 | 0.83 | TSHR (0.40) | TSHRSMN1; SMN2RAB9AALDH1A1ALOX12 | |
| SCHEMBL5091798 | 0.78 | TSHR (0.44) | TSHRSMN1; SMN2RAB9AALDH1A1ALOX12 | |
| SCHEMBL43959 | 0.77 | TSHR (0.39) | TSHRSMN1; SMN2RAB9AALDH1A1ALOX12 | |
| Hydrochloric Acid SCHEMBL17595174 | 0.76 | TSHR (0.38) | TSHRSMN1; SMN2RAB9AALDH1A1ALOX12 | |
| SCHEMBL16438029 | 0.74 | TSHR (0.37) | TSHRSMN1; SMN2RAB9AALDH1A1ALOX12 | |
| SCHEMBL8859577 | 0.74 | RAB9A (0.36) | TSHRSMN1; SMN2RAB9AALDH1A1ALOX12 | |
| Hydroxyamine SCHEMBL3213770 | 0.74 | TSHR (0.37) | TSHRSMN1; SMN2RAB9AALDH1A1ALOX12 | |
| SCHEMBL43850 | 0.73 | SMN1; SMN2 (0.38) | TSHRSMN1; SMN2RAB9AALDH1A1ALOX12 | |
| SCHEMBL4381249 | 0.72 | TSHR (0.38) | TSHRSMN1; SMN2RAB9AALDH1A1ALOX12 | |
| SCHEMBL24287571 | 0.71 | SMN1; SMN2 (0.46) | TSHRSMN1; SMN2ALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050276863-A1 | Methods for treatment of aneurysmal tissue | MEDTRONIC VASCULAR, INC. (US) | 2005-12-15 | — | — | US | claimed |
| EP-1602925-A2 | Methods for treatment of aneurysmal tissue | Medtronic Vascular, Inc. (US) | 2005-12-07 | — | — | EP | claimed |
| EP-1602925-B1 | System for treatment of aneurysmal tissue | MEDTRONIC VASCULAR INC (US) | 2008-04-30 | — | — | EP | disclosed |
| US-20050276863-A1 | Methods for treatment of aneurysmal tissue | MEDTRONIC VASCULAR, INC. (US) | 2005-12-15 | — | — | US | disclosed |
| EP-1602925-A2 | Methods for treatment of aneurysmal tissue | Medtronic Vascular, Inc. (US) | 2005-12-07 | — | — | EP | disclosed |