Fluoride

Fluoride

SCHEMBL18979129

F.F.F.Fc1ccccc1Br

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.43
ALDH1A1 P00352 4/20 0.41
ACHE P22303 1/20 0.41
NFE2L2 Q16236 3/20 0.39
TAAR1 Q96RJ0 2/20 0.39
MAPK1 P28482 1/20 0.38
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
KMT2A Q03164 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
KCNN4 O15554 1/20 0.34
MAOB P27338 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL31239586 1.00 HTT (0.43) HTTALDH1A1ACHENFE2L2TAAR1
SCHEMBL29572769 0.97
SCHEMBL153356 0.97
SCHEMBL2707293 0.94
Hydrogen Sulfide SCHEMBL28144546 0.94
Water SCHEMBL28144539 0.94
Ammonia Solution, Strong SCHEMBL2165678 0.94
Potassium Ion SCHEMBL11777963 0.91 HTT (0.47) HTTALDH1A1ACHENFE2L2TAAR1
Nitrogen SCHEMBL27817436 0.91 HTT (0.42) HTTALDH1A1ACHENFE2L2TAAR1
Ethyne SCHEMBL27805472 0.91 HTT (0.42) HTTALDH1A1ACHENFE2L2TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220000112-A1 DIARYLIMIDAZOLE COMPOUND AND HARMFUL ORGANISM CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2022-01-06 US disclosed
EP-3766871-A1 DIARYLIMIDAZOLE COMPOUND AND PEST CONTROL AGENT Nippon Soda Co., Ltd. (JP) 2021-01-20 EP disclosed
EP-3181552-B1 DIARYL IMIDAZOLE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO (JP) 2020-10-21 EP disclosed
US-20200187501-A1 DIARYLIMIDAZOLE COMPOUND AND HARMFUL ORGANISM CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2020-06-18 US disclosed
US-20180289006-A1 DIARYLIMIDAZOLE COMPOUND AND HARMFUL ORGANISM CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2018-10-11 US disclosed
US-10021880-B2 Diarylimidazole compound and harmful organism control agent NIPPON SODA CO., LTD. (JP) 2018-07-17 US disclosed
US-20170223958-A1 DIARYLIMIDAZOLE COMPOUND AND HARMFUL ORGANISM CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2017-08-10 US disclosed
EP-3181552-A1 DIARYL IMIDAZOLE COMPOUND AND PEST CONTROL AGENT Nippon Soda Co., Ltd. (JP) 2017-06-21 EP disclosed
CN-101068797-A Carboxylic acid derivative containing thiazole ring and pharmaceutical use thereof MITSUBISHI PHARMA CORP (JP) 2007-11-07 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10021880-B2 Diarylimidazole compound and harmful organism control agent NOX1, L3MBTL1, MRM1 HTT 4853/4885ALDH1A1 114/4885ACHE 2246/4885
US-20200187501-A1 DIARYLIMIDAZOLE COMPOUND AND HARMFUL ORGANISM CONTROL AGENT NOX1, L3MBTL1, MRM1 HTT 4853/4885ALDH1A1 114/4885ACHE 2246/4885
US-20180289006-A1 DIARYLIMIDAZOLE COMPOUND AND HARMFUL ORGANISM CONTROL AGENT NOX1, L3MBTL1, MRM1 HTT 4853/4885ALDH1A1 114/4885ACHE 2246/4885
US-20220000112-A1 DIARYLIMIDAZOLE COMPOUND AND HARMFUL ORGANISM CONTROL AGENT NOX1, L3MBTL1, MRM1 HTT 4853/4885ALDH1A1 114/4885ACHE 2246/4885
US-20170223958-A1 DIARYLIMIDAZOLE COMPOUND AND HARMFUL ORGANISM CONTROL AGENT NOX1, L3MBTL1, MRM1 HTT 4853/4885ALDH1A1 114/4885ACHE 2246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.