SCHEMBL18979409

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31672278	1.00	CHEK2 (0.45)	CHEK2CTSCABCB1ABCC1CYP2A6
	SCHEMBL18979448	0.86	HDAC1 (0.46)	CHEK2CTSCABCB1ABCC1CYP2A6
	SCHEMBL31672284	0.81	DEGS1 (0.62)	ABCB1ABCC1RAB9AHCAR3DEGS1
	SCHEMBL18979459	0.81	DEGS1 (0.62)	ABCB1ABCC1RAB9AHCAR3DEGS1
	SCHEMBL31672281	0.81	RAB9A (0.53)	ABCB1ABCC1TP53TSHRNFKB1
	SCHEMBL18979486	0.81	RAB9A (0.53)	ABCB1ABCC1TP53TSHRNFKB1
	SCHEMBL18979396	0.78	CHEK2 (0.47)	CHEK2CYP2A6CYP2E1CYP2B6
	SCHEMBL17027797	0.74	RAB9A (0.66)	TP53TSHRRAB9AKDM4E
	SCHEMBL17027778	0.73	DEGS1 (0.47)	ABCB1ABCC1DEGS1
	SCHEMBL17027836	0.72	ABCB1 (0.49)	ABCB1ABCC1TP53RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.