SCHEMBL18979486

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31672281	1.00	RAB9A (0.53)	RAB9ANPC1SMN1; SMN2TP53NPSR1
	SCHEMBL18979409	0.81	CHEK2 (0.45)	RAB9ASMN1; SMN2TP53ABCB1ABCC1
	SCHEMBL31672278	0.81	CHEK2 (0.45)	RAB9ASMN1; SMN2TP53ABCB1ABCC1
	SCHEMBL18979459	0.80	DEGS1 (0.62)	RAB9ANPC1ABCB1ABCC1HCAR3
	SCHEMBL31672284	0.80	DEGS1 (0.62)	RAB9ANPC1ABCB1ABCC1HCAR3
	SCHEMBL18979418	0.73	DYRK1A (0.46)	RAB9ANPC1TP53ABCB1ABCC1
	SCHEMBL17027836	0.73	ABCB1 (0.49)	RAB9ANPC1SMN1; SMN2TP53ABCB1
	SCHEMBL17027797	0.73	RAB9A (0.66)	RAB9ANPC1TP53TSHRKDM4E
	SCHEMBL17027778	0.72	DEGS1 (0.47)	ABCB1ABCC1DEGS1
	SCHEMBL18979432	0.71	KCNQ3 (0.45)	RAB9ANPC1TP53ABCB1ABCC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.