SCHEMBL18979433

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31672286	1.00	DEGS1 (0.53)	DEGS1RAB9AKMT2AKDM4EWNT3A
	SCHEMBL18996621	0.88	DEGS1 (0.63)	DEGS1RAB9AKMT2AKDM4EWNT3A
	SCHEMBL18979442	0.88	DEGS1 (0.63)	DEGS1RAB9AKMT2ASMN1; SMN2MEN1
	SCHEMBL31672287	0.86	DEGS1 (0.68)	DEGS1RAB9AKMT2ASMN1; SMN2ABCB1
	SCHEMBL18979445	0.86	DEGS1 (0.68)	DEGS1RAB9AKMT2ASMN1; SMN2ABCB1
	SCHEMBL18979502	0.83	DEGS1 (0.58)	DEGS1RAB9AKMT2AKDM4EABCB1
	SCHEMBL18979448	0.83	HDAC1 (0.46)	DEGS1SMN1; SMN2ABCB1ABCC1HDAC1
	SCHEMBL18979481	0.82	RAB9A (0.52)	DEGS1RAB9AKMT2AKDM4EWNT3A
	SCHEMBL31672285	0.82	RAB9A (0.52)	DEGS1RAB9AKMT2AKDM4EWNT3A
	SCHEMBL18979398	0.81	HDAC1 (0.46)	DEGS1RAB9AWNT3ASMN1; SMN2ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.