SCHEMBL18979481

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31672285	1.00	RAB9A (0.52)	RAB9ANPC1KMT2AMEN1GRM5
	SCHEMBL23406055	0.89	SMN1; SMN2 (0.65)	RAB9ANPC1KMT2AMEN1GRM5
	SCHEMBL20641476	0.89	RAB9A (0.66)	RAB9ANPC1KMT2AMEN1GRM5
	SCHEMBL23405893	0.88	RAB9A (0.67)	RAB9ANPC1KMT2AMEN1GRM5
	SCHEMBL18996621	0.85	DEGS1 (0.63)	RAB9ANPC1KMT2AMEN1KDM4E
	SCHEMBL3408514	0.84	RAB9A (0.72)	RAB9ANPC1KMT2AMEN1GRM5
	SCHEMBL23406072	0.84	DEGS1 (0.63)	RAB9ANPC1KMT2AMEN1SMN1; SMN2
	SCHEMBL29744146	0.84	DEGS1 (0.63)	RAB9ANPC1KMT2AMEN1SMN1; SMN2
	SCHEMBL23405932	0.83	GRM5 (0.64)	RAB9ANPC1KMT2AMEN1GRM5
	SCHEMBL23405976	0.83	KDM4E (0.59)	RAB9ANPC1KMT2AMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.