SCHEMBL18979439

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30958673	0.85	USP30 (0.62)	USP30PIK3CDBTKALDH1A1NPC1
	SCHEMBL28964756	0.85	USP30 (0.62)	USP30PIK3CDBTKALDH1A1NPC1
	SCHEMBL28964759	0.85	USP30 (0.62)	USP30PIK3CDBTKALDH1A1NPC1
	SCHEMBL15584486	0.83	ALDH1A1 (0.55)	USP30BTKALDH1A1NPC1MAPT
	SCHEMBL13313526	0.83	ALDH1A1 (0.55)	USP30BTKALDH1A1NPC1MAPT
	SCHEMBL28513447	0.79	USP30 (0.70)	USP30PIK3CDBTKHPGDSGPR119
	SCHEMBL28513449	0.79	USP30 (0.70)	USP30PIK3CDBTKHPGDSGPR119
	SCHEMBL18996615	0.79	KDM4E (0.39)	—
	SCHEMBL1469152	0.78	USP30 (0.49)	USP30PIK3CDBTKALDH1A1NPC1
	SCHEMBL17027776	0.78	USP30 (0.55)	USP30BTKALDH1A1NPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.