Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18979780 | 0.90 | HDAC1 (0.44) | ALDH1A1HSD17B10FFAR1MAPTMAPK1 | |
| SCHEMBL18979782 | 0.87 | RXFP1 (0.47) | ALDH1A1FFAR1MAPTLMNARECQL | |
| SCHEMBL4799199 | 0.77 | PTGER1 (0.37) | KEAP1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7477617 | 0.77 | ALDH1A1 (0.47) | KEAP1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL18979838 | 0.72 | CA1 (0.42) | KDM4EALDH1A1HSD17B10LMNAESR1 | |
| SCHEMBL543197 | 0.72 | CA1 (0.36) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL1664496 | 0.72 | LMNA (0.44) | KDM4EALDH1A1MAPTL3MBTL1POLB | |
| SCHEMBL24709934 | 0.71 | ALDH1A1 (0.40) | KDM4EALDH1A1HSD17B10HPGDL3MBTL1 | |
| SCHEMBL18979865 | 0.71 | HDAC1 (0.42) | ALDH1A1FFAR1MAPTMAPK1KMT2A | |
| SCHEMBL10515679 | 0.69 | NPC1 (0.34) | KDM4EALDH1A1TDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170176470-A1 | DETECTION OF CARBOXYALKYLPYRROLE OR PENTYLPYRROLE ETHANOLAMINE PHOSPHOLIPIDS | UNIV CASE WESTERN RESERVE (US) | 2017-06-22 | — | — | US | disclosed |