Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | EEF2K | O00418 | 3/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28080811 | 0.81 | KCNQ2 (0.47) | CES2CES1OPRM1ABCB11CHRM2 | |
| SCHEMBL1404415 | 0.78 | EEF2K (0.36) | CES2CES1OPRM1CNR2EEF2K | |
| SCHEMBL13193369 | 0.75 | KMT2A (0.41) | CES2CES1CNR2EEF2KKCNQ2 | |
| SCHEMBL15444204 | 0.74 | NPC1 (0.40) | CES2CES1KCNQ2MEN1KMT2A | |
| SCHEMBL12809865 | 0.73 | CES2 (0.54) | CES2CES1OPRM1ABCB11CHRM2 | |
| SCHEMBL12126396 | 0.73 | CES2 (0.54) | CES2CES1OPRM1ABCB11CHRM2 | |
| SCHEMBL5861434 | 0.72 | KMT2A (0.40) | CES2CES1KCNQ2MEN1KMT2A | |
| SCHEMBL3318078 | 0.72 | CES2 (0.41) | CES2CES1OPRM1ABCB11CHRM2 | |
| SCHEMBL242256 | 0.72 | CES2 (0.41) | CES2CES1OPRM1ABCB11CHRM2 | |
| SCHEMBL10005655 | 0.72 | HIF1A (0.46) | CES2CES1OPRM1ABCB11CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2501701-A1 | METHOD OF PRODUCING HIGHLY PURE PRASUGREL AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | Zentiva, K.S. (CZ) | 2012-09-26 | — | — | EP | disclosed |
| WO-2011057592-A1 | METHOD OF PRODUCING HIGHLY PURE PRASUGREL AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | ZENTIVA, K.S. (CZ) | 2011-05-19 | — | — | WO | disclosed |