Sugi Predict

Sugi Predict / Compounds / SCHEMBL242256

SCHEMBL242256

SCHEMBL242256

O=C(C1CC1)C(Br)c1ccccc1F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CES2 O00748 2/20 0.41
▸ CES1 P23141 2/20 0.41
▸ GAA P10253 2/20 0.41
▸ NOTUM Q6P988 1/20 0.39
▸ OPRM1 P35372 2/20 0.38
▸ ABCB11 O95342 1/20 0.38
▸ CHRM2 P08172 1/20 0.38
▸ ADORA3 P0DMS8 1/20 0.38
▸ AR P10275 1/20 0.38
▸ P2RY12 Q9H244 1/20 0.38
▸ MEN1 O00255 2/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ ALDH1A1 P00352 1/20 0.37
▸ CYP3A4 P08684 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ CYP2C9 P11712 1/20 0.37
▸ POLB P06746 1/20 0.36
▸ CNR2 P34972 1/20 0.36
▸ CHRNB2 P17787 1/20 0.35
▸ CHRNB4 P30926 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12809865 0.81 CES2 (0.54) CES2CES1GAANOTUMOPRM1
SCHEMBL12126396 0.81 CES2 (0.54) CES2CES1GAANOTUMOPRM1
SCHEMBL8678425 0.81 OPRL1 (0.41) NOTUMOPRM1KMT2ACYP2C9
SCHEMBL3736079 0.80 CES2 (0.44) CES2CES1GAAKMT2AALDH1A1
SCHEMBL8677107 0.80 CES2 (0.42) CES2CES1GAAMEN1KMT2A
SCHEMBL3730553 0.80 CES2 (0.44) CES2CES1GAAOPRM1POLB
SCHEMBL3318078 0.79 CES2 (0.41) CES2CES1GAANOTUMOPRM1
SCHEMBL986053 0.79 CES2 (0.41) CES2CES1GAANOTUMOPRM1
SCHEMBL10005655 0.79 HIF1A (0.46) CES2CES1NOTUMOPRM1ABCB11
SCHEMBL3733998 0.78 CES2 (0.42) CES2CES1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119468518-A Graphene coating heat collecting tube applied to photo-thermal power generation 鄂尔多斯应用技术学院 2025-02-18 — — CN claimed
CN-109311907-B Preparation method of high-purity prasugrel 吉瑞工厂 2022-09-13 — — CN claimed
CN-110950885-B Method and device for continuously preparing prasugrel intermediate through countercurrent extraction 南京恒道医药科技有限公司 2022-04-15 — — CN claimed
EP-3475288-B1 PROCESS FOR THE PREPARATION OF HIGH-PURITY PRASUGREL RICHTER GEDEON NYRT (HU) 2021-11-03 — — EP claimed
CN-110950885-A Method and device for continuously preparing prasugrel intermediate through countercurrent extraction 南京恒道医药科技有限公司 2020-04-03 — — CN claimed
CN-106752915-B Nanoscale metal ceramic solar heat-absorbing coating material and preparation method thereof 上海电力学院 2019-12-27 — — CN claimed
US-20190211029-A1 PROCESS FOR THE PREPARATION OF HIGH-PURITY PRASUGREL RICHTER GEDEON NYRT. (HU) 2019-07-11 — — US claimed
EP-3475288-A1 PROCESS FOR THE PREPARATION OF HIGH-PURITY PRASUGREL Richter Gedeon Nyrt. (HU) 2019-05-01 — — EP claimed
WO-2017221187-A1 PROCESS FOR THE PREPARATION OF HIGH-PURITY PRASUGREL RICHTER GEDEON NYRT. (HU) 2017-12-28 — — WO claimed
EP-2471795-B1 METHOD FOR PREPARING PRASUGREL ZHEJIANG HUAHAI PHARM CO LTD (CN) 2016-04-20 — — EP claimed
EP-2499147-A2 IMPROVED PROCESSES FOR PREPARING PRASUGREL AND PHARMACEUTICALLY ACCEPTABLE SALTS THEROEOF MSN Laboratories Limited (IN) 2012-09-19 — — EP claimed
US-20120202066-A1 Processes For Preparing Prasugrel And Pharmaceutically Acceptable Salts Thereof MSN LABORATORIES LIMITED (IN) 2012-08-09 — — US claimed
EP-2471795-A1 METHOD FOR PREPARING PRASUGREL Zhejiang Huahai Pharmaceutical Co., Ltd. (CN) 2012-07-04 — — EP claimed
US-20120142927-A1 METHOD FOR PREPARING PRASUGREL ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTD. (CN) 2012-06-07 — — US claimed
WO-2012052788-A1 METHOD FOR PREPARING PHARMACEUTICALLY ACTIVE INGREDIENT AND INTERMEDIATES THEREOF EGIS GYÓGYSZERGYÁR NYILVÁNOSAN MŰKÖDŐ RÉSZVÉNYTÁRSASÁG (HU) 2012-04-26 — — WO claimed
WO-2012018791-A2 PREPARATION OF PRASUGREL HYDROCHLORIDE DR. REDDY'S LABORATORIES LTD. (IN) 2012-02-09 — — WO claimed
WO-2012001486-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF PRASUGREL HYDROCHLORIDE AND ITS INTERMEDIATES MAYUKA LABS PVT. LTD. (IN) 2012-01-05 — — WO claimed
WO-2011092720-A2 PHARMACEUTICAL COMPOSITION OF PRASUGREL AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS MSN LABORATORIES LIMITED (IN) 2011-08-04 — — WO claimed
WO-2011042918-A2 NOVEL AND IMPROVED PROCESSES FOR THE PREPARATION OF PRASUGREL, ITS INTERMEDIATES AND PHARMACEUTICALLY ACCEPTABLE SALTS MSN LABORATORIES LIMITED (IN) 2011-04-14 — — WO claimed
WO-2009066326-A2 IMPROVED PROCESS FOR THE PREPARATION OF PRASUGREL AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS MSN LABORATORIES LIMITED (IN) 2009-05-28 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120142927-A1 METHOD FOR PREPARING PRASUGREL FDPS, PFAS, PF4 CES2 243/4885CES1 457/4885GAA 929/4885
US-20190211029-A1 PROCESS FOR THE PREPARATION OF HIGH-PURITY PRASUGREL CYP3A5, CYP4B1, AGPS CES2 723/4885CES1 159/4885GAA 1739/4885
US-20120202066-A1 Processes For Preparing Prasugrel And Pharmaceutically Acceptable Salts Thereof SF1, PFKP, CYP2F1 CES2 2975/4885CES1 245/4885GAA 1032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.