Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18979822 | 0.95 | KMT2A (0.46) | SLC22A6FOLH1KMT2AMAPTLMNA | |
| SCHEMBL18979819 | 0.89 | ALDH1A1 (0.41) | LMNAALDH1A1SMN1; SMN2ACECYP1A2 | |
| SCHEMBL5101571 | 0.84 | LMNA (0.42) | SLC22A6KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL12723334 | 0.84 | ALDH1A1 (0.42) | SLC22A6FOLH1LMNAALDH1A1TSHR | |
| SCHEMBL4080821 | 0.80 | ACE (0.43) | SLC22A6FOLH1KMT2AMAPTLMNA | |
| SCHEMBL10334572 | 0.76 | LMNA (0.46) | SLC22A6FOLH1KMT2ALMNAALDH1A1 | |
| SCHEMBL2578186 | 0.75 | LMNA (0.40) | SLC22A6FOLH1KMT2ALMNAALDH1A1 | |
| SCHEMBL18900660 | 0.75 | TDP1 (0.36) | KMT2ALMNASMN1; SMN2POLBUSP2 | |
| SCHEMBL5668522 | 0.74 | LMNA (0.50) | SLC22A6FOLH1KMT2ALMNAALDH1A1 | |
| SCHEMBL19417428 | 0.73 | KDM4E (0.38) | SMN1; SMN2POLBCAMK2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170176470-A1 | DETECTION OF CARBOXYALKYLPYRROLE OR PENTYLPYRROLE ETHANOLAMINE PHOSPHOLIPIDS | UNIV CASE WESTERN RESERVE (US) | 2017-06-22 | — | — | US | disclosed |