Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PEPD | P12955 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL28124837 | 1.00 | LMNA (0.56) | LMNASLC34A1CA4KMT2AKDM4E | |
| Phosphoric Acid SCHEMBL29215422 | 0.96 | LMNA (0.53) | LMNASLC34A1CA4KMT2AKDM4E | |
| Phosphoric Acid SCHEMBL28109838 | 0.96 | LMNA (0.53) | LMNASLC34A1CA4KMT2AKDM4E | |
| Phosphoric Acid SCHEMBL27610161 | 0.96 | LMNA (0.53) | LMNASLC34A1CA4KMT2AKDM4E | |
| Phosphoric Acid SCHEMBL28557229 | 0.96 | SLC34A1 (0.53) | LMNASLC34A1CA4KMT2AKDM4E | |
| Phosphoric Acid SCHEMBL28662987 | 0.93 | SLC34A1 (0.60) | LMNASLC34A1CA4KMT2AKDM4E | |
| Phosphoric Acid SCHEMBL10821649 | 0.92 | SLC34A1 (0.57) | LMNASLC34A1CA4KMT2AKDM4E | |
| Phosphoric Acid SCHEMBL28072292 | 0.92 | SLC34A1 (0.57) | LMNASLC34A1CA4KMT2AKDM4E | |
| Phosphoric Acid SCHEMBL28006434 | 0.92 | SLC34A1 (0.57) | LMNASLC34A1CA4KMT2AKDM4E | |
| Phosphoric Acid SCHEMBL28520927 | 0.89 | SLC34A1 (0.53) | LMNASLC34A1CA4KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108295033-A | A kind of injection pemetrexed disodium freeze-dried powder | 宁波蒙曼生物科技有限公司 | 2018-07-20 | — | — | CN | claimed |
| US-10813860-B2 | Leave-in chemical foam comprising benzoyl peroxide | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2020-10-27 | — | — | US | disclosed |
| CN-110499053-A | A kind of water-based industrial paint multifunctional assistant | JUNNENG CHEMICAL LONGNAN CO LTD | 2019-11-26 | — | — | CN | disclosed |
| US-10449175-B2 | Rinse-off chemical mousse containing benzoyl peroxide | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2019-10-22 | — | — | US | disclosed |
| CN-108295033-B | A kind of injection pemetrexed disodium freeze-dried powder | 舒泰神（北京）生物制药股份有限公司 | 2019-03-29 | — | — | CN | disclosed |
| CN-108295033-A | A kind of injection pemetrexed disodium freeze-dried powder | 宁波蒙曼生物科技有限公司 | 2018-07-20 | — | — | CN | disclosed |
| US-20180185283-A1 | NON-RINSE CHEMICAL MOUSSE CONTAINING ADAPALENE AND BENZOYL PEROXIDE | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2018-07-05 | — | — | US | disclosed |
| US-20170172972-A1 | RINSE-OFF CHEMICAL MOUSSE CONTAINING BENZOYL PEROXIDE | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2017-06-22 | — | — | US | disclosed |
| US-20170172877-A1 | LEAVE-IN CHEMICAL FOAM COMPRISING BENZOYL PEROXIDE | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2017-06-22 | — | — | US | disclosed |