Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL390339 | 0.81 | GPR119 (0.73) | GPR119PDGFRB | |
| SCHEMBL385801 | 0.67 | GPR119 (0.81) | GPR119 | |
| SCHEMBL388663 | 0.65 | GPR119 (1.00) | GPR119 | |
| SCHEMBL5264267 | 0.63 | GPR119 (0.63) | GPR119PDGFRB | |
| SCHEMBL1674106 | 0.62 | GPR119 (0.59) | GPR119MAPTMAPK1 | |
| SCHEMBL27632164 | 0.61 | GPR119 (0.46) | GPR119 | |
| SCHEMBL388439 | 0.60 | GPR119 (0.65) | GPR119MAPTPDGFRA | |
| SCHEMBL1070108 | 0.59 | GPR119 (0.79) | GPR119MAPT | |
| SCHEMBL12312090 | 0.59 | ALDH1A1 (0.56) | MAPT | |
| SCHEMBL30832672 | 0.59 | ALDH1A1 (0.56) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2322152-A1 | Method of preparing a composition comprising a GPR119 agonist | Arena Pharmaceuticals, Inc. (US) | 2011-05-18 | — | — | EP | disclosed |