Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.40 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5374418 | 0.89 | TSHR (0.48) | ATMCES1CES2TSHRHPGD | |
| SCHEMBL6916133 | 0.87 | CES1 (0.46) | CES1CES2TSHRALDH1A1TP53 | |
| SCHEMBL3862259 | 0.83 | CES1 (0.42) | CES1CES2TSHRALDH1A1TP53 | |
| SCHEMBL6057358 | 0.83 | CES1 (0.42) | CES1CES2TSHRALDH1A1TP53 | |
| SCHEMBL1061914 | 0.83 | TSHR (0.47) | CES1CES2TSHRHPGDALDH1A1 | |
| SCHEMBL7520087 | 0.83 | HCAR2 (0.37) | ATMHCAR2TSHRHPGDALDH1A1 | |
| SCHEMBL2438115 | 0.83 | HCAR2 (0.37) | ATMHCAR2TSHRHPGDALDH1A1 | |
| SCHEMBL9640893 | 0.82 | TSHR (0.46) | CES1CES2TSHRHPGDALDH1A1 | |
| SCHEMBL9651226 | 0.82 | TSHR (0.46) | CES1CES2TSHRHPGDALDH1A1 | |
| SCHEMBL9743325 | 0.82 | CES1 (0.41) | CES1CES2TSHRALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4606909-A | CONTROLLED RELEASE, SPARINGLY SOLUBLE ACTIVE CORE WITH ERODABLE ENERIC COATING | A/S ALFRED BENZON (DK) | 1986-08-19 | — | — | US | claimed |
| EP-2632441-A2 | COMPOSITIONS OF (-)-17-(CYCLOBUTYLMETHYL) MORPHINAN-3, 14-DIOL | Babul, Najib (US) | 2013-09-04 | — | — | EP | disclosed |
| WO-2012058695-A2 | COMPOSITIONS OF (-)-17-(CYCLOBUTYLMETHYL) MORPHINAN-3, 14-DIOL | BABUL NAJIB (US) | 2012-05-03 | — | — | WO | disclosed |
| WO-2011061763-A2 | POLYMERIC BASED ANTICORROSIVE COATINGS | JOSHI KUSUM (IN) | 2011-05-26 | — | — | WO | disclosed |
| US-20010024651-A1 | Method for inducing a systemic immune response to an antigen | ORAL VACCINE TECHNOLOGIES, INC. | 2001-09-27 | — | — | US | disclosed |