Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | LGALS3 | P17931 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.43 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.43 |
| ▸ | CD69 | Q07108 | 2/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.39 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.38 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30644644 | 0.90 | MAPK1 (0.56) | MAPK1LGALS3ALDH1A1THRBKDM4E | |
| SCHEMBL23031946 | 0.90 | MAPK1 (0.56) | MAPK1LGALS3ALDH1A1THRBKDM4E | |
| SCHEMBL8000037 | 0.88 | MAPK1 (0.66) | MAPK1LGALS3ALDH1A1THRBKDM4E | |
| SCHEMBL11425414 | 0.88 | MAPK1 (0.66) | MAPK1LGALS3ALDH1A1THRBKDM4E | |
| SCHEMBL8000040 | 0.88 | MAPK1 (0.66) | MAPK1LGALS3ALDH1A1THRBKDM4E | |
| SCHEMBL7888480 | 0.88 | MAPK1 (0.66) | MAPK1LGALS3ALDH1A1THRBKDM4E | |
| SCHEMBL7888483 | 0.88 | MAPK1 (0.66) | MAPK1LGALS3ALDH1A1THRBKDM4E | |
| SCHEMBL13308281 | 0.87 | MAPK1 (0.56) | MAPK1LGALS3ALDH1A1THRBKDM4E | |
| SCHEMBL13491439 | 0.87 | MAPK1 (0.56) | MAPK1LGALS3ALDH1A1THRBKDM4E | |
| SCHEMBL25043094 | 0.87 | MAPK1 (0.56) | MAPK1LGALS3ALDH1A1THRBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10378034-B2 | Use of a N-acetylneuraminate lyase derived from the bacterium Aliivibrio salmonicida in the production of neuraminic acid and derivatives thereof | Universitetet I Tromsø—Norges Arktiske Universitet (NO) | 2019-08-13 | — | — | US | disclosed |
| US-20170175155-A1 | USE OF A N-ACETYLNEURAMINATE LYASE DERIVED FROM THE BACTERIUM ALIIVIBRIO SALMONICIDA IN THE PRODUCTION OF NEURAMINIC ACID AND DERIVATIVES THEREOF | UNIVERSITETET I TROMSØ - NORGES ARKTISKE UNIVERSITET (NO) | 2017-06-22 | — | — | US | disclosed |