Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.39 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CD69 | Q07108 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA4 | P22748 | 3/20 | 0.38 |
| ▸ | CA5A | P35218 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23031946 | 1.00 | MAPK1 (0.56) | MAPK1LMNAKMT2AALDH1A1THRB | |
| SCHEMBL18984599 | 0.90 | MAPK1 (0.55) | MAPK1LMNAALDH1A1THRBLGALS3 | |
| SCHEMBL7888483 | 0.90 | MAPK1 (0.66) | MAPK1LMNAALDH1A1THRBLGALS3 | |
| SCHEMBL8000037 | 0.90 | MAPK1 (0.66) | MAPK1LMNAALDH1A1THRBLGALS3 | |
| SCHEMBL7888480 | 0.90 | MAPK1 (0.66) | MAPK1LMNAALDH1A1THRBLGALS3 | |
| SCHEMBL8000040 | 0.90 | MAPK1 (0.66) | MAPK1LMNAALDH1A1THRBLGALS3 | |
| SCHEMBL11425414 | 0.90 | MAPK1 (0.66) | MAPK1LMNAALDH1A1THRBLGALS3 | |
| SCHEMBL5148124 | 0.85 | LMNA (0.57) | MAPK1LMNAKMT2AALDH1A1THRB | |
| SCHEMBL19477779 | 0.85 | LMNA (0.57) | MAPK1LMNAKMT2AALDH1A1THRB | |
| SCHEMBL20643514 | 0.85 | LMNA (0.57) | MAPK1LMNAKMT2AALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3737384-B1 | METHODS AND COMPOSITIONS FOR PREVENTING AND TREATING CONDITIONS RELATED TO ALPHA-SYNUCLEIN | PUREPHARM INC (CA) | 2023-10-25 | — | — | EP | disclosed |